Status:

RECRUITING

Hepato-pancreato-biliary Abnormalities in Fibrous Dysplasia of Bone/McCune Albright Syndrome

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Fibrous Dysplasia of Bone

Eligibility:

All Genders

18-100 years

Brief Summary

Fibrous dysplasia of bone /McCune Albright syndrome (FD/MAS) is a rare bone disease caused by somatic mutations in GNAS gene. This GNAS mutation predisposes to cancers, including breast cancer, thyroi...

Eligibility Criteria

Inclusion

  • Adults ≥18 years with polyostotic FD/MAS
  • Followed up in the national FD reference center (Lyon) or in a FD French expert center: Angers, Bordeaux, Brest, Caen, Clermont-Ferrand, Lille, Marseille, Montpellier, Nice, Paris, Poitiers, Rennes, Saint-Etienne, Strasbourg.
  • who had an hepato-bilio-pancreatic MRI during their follow-up, since January 2002
  • No objection to data collection

Exclusion

  • Opposition to data collection

Key Trial Info

Start Date :

January 19 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 12 2025

Estimated Enrollment :

545 Patients enrolled

Trial Details

Trial ID

NCT06177327

Start Date

January 19 2024

End Date

December 12 2025

Last Update

February 29 2024

Active Locations (16)

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Page 1 of 4 (16 locations)

1

CHU Angers

Angers, France, 49100

2

Groupe Hospitalier Pellegrin - Chu

Bordeaux, France, 33076

3

CHU de Brest - Hôpital de la Cavale Blanche

Brest, France, 29609

4

Chu de Caen Normandie

Caen, France, 14000