Status:

UNKNOWN

Effectiveness of Accelerated Deep TMS in OCD

Lead Sponsor:

Pamukkale University

Conditions:

Obsessive-Compulsive Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

H-coil high-frequency deep transcranial magnetic stimulation (dTMS) over the medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC) has been approved by the Food and Drug Administration f...

Detailed Description

The current study aimed to investigate the effectiveness and safety of the ITBS protocol, which is applied to the mPFC and ACC for 5 sessions per day with a double-cone coil in treatment-resistant OCD...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of obsessive-compulsive disorder
  • Not having an adequate response to treatment despite the use of an SGI selective serotonin reuptake inhibitors at a sufficient dose and duration (at least 8 weeks) before the planned add-on treatment
  • No dose or active substance changes have been made in the treatment regimen for at least 8 weeks
  • Aged 18-65 years
  • Able to read and write
  • Not having a significant medical or neurological disease

Exclusion

  • Not providing consent to participate in the study
  • Diagnosis of a psychiatric disorder, such as psychotic disorder, bipolar disorder, major depressive disorder \[Hamilton Depression Rating Scale (HDRS) score above 17\], mental retardation, alcohol-substance use disorder, and organic mental disorder (dementia, delirium, and head trauma, etc.)
  • Diagnosis of an important medical or neurological disease (e.g., epilepsy);
  • Mental retardation
  • Illiteracy
  • Having received electroconvulsive therapy (ECT) or TMS within the last six months;
  • Having any prosthesis, such as an implant and pacemaker.

Key Trial Info

Start Date :

December 18 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 18 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06177470

Start Date

December 18 2023

End Date

October 18 2024

Last Update

December 20 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Pamukkale University

Denizli, Turkey (Türkiye), 20160

Effectiveness of Accelerated Deep TMS in OCD | DecenTrialz