Status:
UNKNOWN
Outcome of Regenerative Endodontic Procedure and Root Canal Treatment for the Management of Apical Periodontitis
Lead Sponsor:
Postgraduate Institute of Dental Sciences Rohtak
Conditions:
Apical Periodontitis
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Background Root canal therapy is the primary treatment of choice for necrotic mature teeth with periapical lesions (PRLs), which does not restore the tooth's vitality. Provided that injectable platele...
Detailed Description
Regenerative endodontic procedures (REPs) are biologically based procedures used to replace damaged structures such as dentin and root structures, as well as pulp-dentin complex cells (4, 5). Majority...
Eligibility Criteria
Inclusion
- Consenting healthy adults with age range of 18- 40 years
- Patient presenting with atleast one permanent mandibular molar with necrotic pulp (negative response to sensibility testing by cold and electric pulp test).
- Radiographic evidence of periapical radiolucency of strictly endodontic origin score ≥3 according to the classification of Ørstavik et al (diagnosis of asymptomatic apical periodontitis or chronic apical abscess) with lesion size ≤ 5mm
Exclusion
- Non-restorable teeth or tooth with severe coronal defect where rubber dam isolation is not possible
- Teeth with root fractures or pathological root resorptions
- Teeth with endodontic- periodontal communications
- Patients with generalized chronic periodontitis or periodontal pocket more than 3 mm
- Teeth with previous root canal treatment
- Severe root canal curvatures
- Pregnant or lactating women
- Patients with a history of systemic diseases and/or receiving medications that affect healing or blood coagulation.
Key Trial Info
Start Date :
May 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06179433
Start Date
May 1 2023
End Date
September 1 2024
Last Update
December 21 2023
Active Locations (1)
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1
postgraduate Institute of Dental sciences
Rohtak, Haryana, India, 124001