Status:
RECRUITING
White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease
Lead Sponsor:
IRCCS Policlinico S. Donato
Conditions:
Mild Cognitive Impairment
Alzheimer Disease
Eligibility:
All Genders
65+ years
Brief Summary
This study focuses on assessing and measuring white matter hyperintensities in individuals with amnestic mild cognitive impairment (aMCI) or Alzheimer's disease. Objective: The primary objective of ...
Eligibility Criteria
Inclusion
- Participants diagnosed with amnestic Mild Cognitive Impairment (aMCI) or Alzheimer's Disease (AD) based on clinical assessments.
- Individuals undergoing brain magnetic resonance imaging (MRI) at the IRCCS Policlinico San Donato as part of routine diagnostic procedures.
- Age-matched and gender-matched healthy control subjects for comparison.
Exclusion
- Individuals with cognitive impairment other than amnestic MCI or AD.
- History of significant neurological disorders (other than MCI or AD) that may impact the study outcomes.
- Presence of contraindications for undergoing MRI procedures.
- Any serious medical or psychiatric condition that, in the judgment of the researchers, may interfere with the study participation or compromise the validity of the results.
- Known history of alcohol or substance abuse that may affect cognitive function.
- Inability or unwillingness to provide informed consent.
Key Trial Info
Start Date :
July 21 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT06179680
Start Date
July 21 2022
End Date
December 1 2026
Last Update
July 9 2025
Active Locations (1)
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1
IRCCS Policlinico San Donato
San Donato Milanese, Milano, Italy, 20097