Status:

RECRUITING

Homburg Renal Evaluation Study on the Clinical Utility of Early AKI Diagnosis

Lead Sponsor:

Universität des Saarlandes

Conditions:

Acute Kidney Injury

Eligibility:

All Genders

18+ years

Brief Summary

Critically ill patients are at risk of developing a sudden decrease of kidney function which may be detected by a decrease in urine output or is diagnosed on the basis of blood tests for substances no...

Detailed Description

Urinary dickkopf-3 (uDKK3), a stress-induced renal tubular epithelium-derived glycoprotein, has been identified as a biomarker predicting persistent kidney dysfunction. In this prospective observatio...

Eligibility Criteria

Inclusion

  • Patients treated on the intensive care units of Saarland University Hospital.

Exclusion

  • Patients on renal replacement treatment before admission to the intensive care unit.
  • Patients with chronic kidney disease stage CKD G3b or below.
  • Known kidney disease.
  • Kidney transplantation.
  • Intoxications leading to dialysis treatment.
  • Participation in other clinical trials.

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06180551

Start Date

December 1 2023

End Date

June 1 2027

Last Update

December 22 2023

Active Locations (1)

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1

Universitätsklinikum des Saarlandes

Homburg, Saarland, Germany, 66421