Status:
RECRUITING
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
Lead Sponsor:
University of Utah
Conditions:
Lifestyle Factors
Overweight and Obesity
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin ...
Detailed Description
A randomized controlled trial with real-world sleep extension in adults with overweight and obesity who habitually obtain short sleep duration will be conducted. Group allocation will be 1:1 and resea...
Eligibility Criteria
Inclusion
- Age: 18-45 years old; equal numbers of men and women
- Body mass index (BMI): 27.5-34.9 kg/m2
- Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months
Exclusion
- Clinically diagnosed sleep disorder or major psychiatric illness
- Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease)
- Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5%
- Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications.
- Cancer that has been in remission less than 5 years
- Pregnant/nursing, experiencing menopause or post-menopausal
- Shift-work: current or history of within last year
- Weight change: \>10% of body weight over prior six months
- Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program
- Currently smoking
- Alcohol intake\>14 drinks per week or \>3 drinks per day
Key Trial Info
Start Date :
February 12 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2028
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06180837
Start Date
February 12 2024
End Date
January 1 2028
Last Update
December 20 2024
Active Locations (1)
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1
College of Health Research Complex--University of Utah
Salt Lake City, Utah, United States, 84112