Status:
RECRUITING
Comparing Fluid Responsiveness Assessment Methods in Patients With Impaired Consciousness
Lead Sponsor:
Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Conditions:
Hypotension
Cognitive Impairment
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Hypotension is a significant precursor to unfavorable clinical outcomes. To determine whether infusion therapy can positively impact the management of hypotension, several evaluative tests can be util...
Detailed Description
Hypotension often precedes adverse clinical outcomes, prompting an investigation into the efficacy of infusion therapy in its management. The study employs a variety of tests for assessment, including...
Eligibility Criteria
Inclusion
- Age ≥ 18 years.
- Hospitalization in an intensive care unit
- Level of consciousness on the FOUR scale ≤ 12 points
- Presence of arterial hypotension
- Presence of a central venous catheter or direct indication for catheterization
- The decision of the medical council to include the patient in the study
Exclusion
- Pulmonary edema
- Absence of one or both lower extremities
- Chronic kidney disease according to KDIGO classification ≥ stage 3b
- Acute kidney injury grade 3
- Documented or suspected increased intracranial pressure (cerebral edema, brain compression, hydrocephalus, etc.).
- Presence of mitral valve regurgitation \> grade 1
- Presence of aortic valve regurgitation \> grade 1
- Patients previously enrolled in the "COMPASS" study in the period of 12 preceding hours
Key Trial Info
Start Date :
January 16 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 20 2026
Estimated Enrollment :
222 Patients enrolled
Trial Details
Trial ID
NCT06180902
Start Date
January 16 2024
End Date
May 20 2026
Last Update
February 27 2025
Active Locations (1)
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1
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
Moscow, Russia