Status:

NOT_YET_RECRUITING

Diagnosing and Monitoring Portal Hypertension Non-invasively Using Spleen Stiffness Measurement in Patients With Advanced Chronic Liver Disease: a Prospective Cohort Study

Lead Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Conditions:

Advanced Chronic Liver Disease

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main ques...

Eligibility Criteria

Inclusion

  • Age above 18years old
  • Advanced chronic liver disease (defined as LSM ≥ 10kPa)
  • Ability to provide informed consent

Exclusion

  • Transjugular intrahepatic portosystemic shunt
  • previous liver transplantation
  • Abnormality of the porto-mesenteric system (portal vein thrombosis, splenic vein thrombosis, splenectomy, portal cavernomatous transformation, porto-caval shunts)
  • Hematological malignancy

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2028

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06181409

Start Date

December 1 2023

End Date

December 1 2028

Last Update

December 26 2023

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