Status:

UNKNOWN

Head-to-head Comparison of Positron Nuclide Radio-labeled FAPI and 18F-FDG PET/CT in Patients With Malignant Tumors

Lead Sponsor:

Guangdong Provincial People's Hospital

Conditions:

Renal Cell Carcinoma

Gastric Cancer

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The latest research has found that the use of positron-labeled FAP inhibitors for targeting FAP has achieved very good results in displaying tumor stroma, especially for tumors with poor FDG PET/CT ob...

Detailed Description

At the beginning of 2022, the National Cancer Center released the latest statistical data showing that the incidence rate of malignant tumors in China reached 293.91/100000, and the mortality rate rea...

Eligibility Criteria

Inclusion

  • Patients with high clinical suspicion of malignant tumors;
  • Those who have undergone endoscopic biopsy or puncture biopsy indicating malignant tumors but have not undergone surgery or chemotherapy;
  • Previous history of malignant tumor surgery, suspected of recurrence or distant metastasis;
  • There is a willingness for puncture biopsy or surgery, and there are no contraindications for puncture biopsy or surgery, and there are no contraindications for anesthesia;
  • Sign an informed consent form and undergo a nuclear medicine examination, without any contraindications, with the ability and willingness to participate in the follow-up plan.

Exclusion

  • Those who cannot tolerate puncture biopsy or surgical contraindications;
  • Those who have undergone radiotherapy and chemotherapy in the past 3 months;
  • Individuals who are allergic to multiple drugs or foods;
  • Those who refuse nuclear medicine examinations;
  • Those who do not agree to sign an informed consent form and are unable or willing to follow up.

Key Trial Info

Start Date :

January 11 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06182644

Start Date

January 11 2024

End Date

September 1 2025

Last Update

January 22 2024

Active Locations (1)

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1

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China, 510080