Status:

UNKNOWN

Evolution of the 6-minute Walk Test in Patients Treated With ELEXACAFTOR / TEZACAFTOR / IVACAFTOR

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

12+ years

Brief Summary

The aim of the study is to identify a link between the new CFTR modulators and physical activity in cystic fibrosis patients. The triple combination of CFTR modulators (ELEXACAFTOR / TEZACAFTOR/ IVAC...

Eligibility Criteria

Inclusion

  • Patients aged ≥ 12 years with cystic fibrosis, heterozygous for the F508del mutation of the CFTR gene, treated with ELEXACAFTOR/ TEZACAFTOR/ IVACAFTOR.
  • Patients followed in the respiratory diseases department of the Renee Sabran Hospital
  • 6-minute walked test performed in the year preceding initiation of ELEXACAFTOR / TEZACAFTOR/ IVACAFTOR
  • 6-minute walked test performed after treatment initiation (between the 3rd month and the 14th month)
  • No opposition to participation

Exclusion

  • \- Age \< 12 years
  • Pregnancy
  • Discontinuation or reduction in dosage of ELEXACAFTOR/ TEZACAFTOR/ IVACAFTOR
  • Patients objecting to the use of their data for research purposes

Key Trial Info

Start Date :

August 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2024

Estimated Enrollment :

73 Patients enrolled

Trial Details

Trial ID

NCT06184763

Start Date

August 1 2023

End Date

November 1 2024

Last Update

December 28 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Respiratory diseases department, Renee Sabran Hospital (Hospices civils de Lyon)

Giens, France, 83406

Evolution of the 6-minute Walk Test in Patients Treated With ELEXACAFTOR / TEZACAFTOR / IVACAFTOR | DecenTrialz