Status:

UNKNOWN

Selective Serotonin Reuptake Inhibitors, Fluoxetine Versus the Standard Oral Desmopressin for Management of Mono-symptomatic Nocturnal Enuresis.

Lead Sponsor:

Fayoum University Hospital

Conditions:

Nocturnal Enuresis

Enuresis

Eligibility:

All Genders

8-16 years

Phase:

NA

Brief Summary

To determine whether there is a role for the selective serotonin reuptake inhibitors fluoxetine versus desmopressin in the treatment of nocturnal enuresis in children who have not responded to standar...

Eligibility Criteria

Inclusion

  • Age ≥ 7 years
  • Severe enuresis with at least (50%) seven wet nights out of 14
  • Failed treatment
  • The enuresis alarm was either ineffective or considered impractical due to the family circumstances.

Exclusion

  • Underlying renal, urologic, neurologic, endocrinologic, or cardiac conditions
  • Patients with psychiatric disorders and behavioral disorders including depression, attention-deficit/hyperactivity disorder.
  • Untreated constipation
  • Contraindications to fluoxetine or desmopressin treatment

Key Trial Info

Start Date :

December 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06185361

Start Date

December 1 2022

End Date

March 1 2024

Last Update

December 29 2023

Active Locations (1)

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1

Faculty of medicine, Fayoum University

Al Fayyum, Egypt, 63514