Status:

RECRUITING

The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks

Lead Sponsor:

Ziekenhuis Oost-Limburg

Conditions:

Hallux Valgus

Anesthesia

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair. Many factors influence the onset and duration ...

Detailed Description

This study aims to evaluate the differential effects of 0.25%, 0.5%, and 1% ropivacaine on the onset time and duration of ultrasound-guided ankle blocks in patients having forefoot surgery for anesthe...

Eligibility Criteria

Inclusion

  • Provide signed and dated informed consent
  • Age 18 to 75 years, scheduled for elective forefoot surgery for hallux valgus repair under unilateral ankle block at ZOL Genk
  • ASA physical I-II-III
  • Able to ambulate (ability to walk independently, with or without assistive devices)
  • Able to learn and perform study sensory and motor assessment by exhibiting sensitivity to pinprick, cold, and light touch (tested beforehand with pinprick/cold/ light touch sensation test) as the patient will have to perform these sensory and motor assessments by him/herself at home at postoperative day 0 to 2

Exclusion

  • Language barrier
  • Preexisting lower extremity neuropathy
  • Contraindications to ankle block (local infection, edema, burn, soft tissue trauma, or distorted anatomy with scarring in the area of block placement)
  • Contraindications for use of NSAIDs
  • Allergy to local anesthetics
  • Uncontrolled anxiety, psychiatric or neurological disorder that might interfere with study assessment
  • Weight below 50 kg based on a maximum dose of 3 mg/kg ropivacaine and a maximum dose of 150 mg ropivacaine.
  • Preoperative use of opioids or gabapentin less than 3 days before surgery
  • Contraindications for use of paracetamol
  • Contraindications for use of tramadol

Key Trial Info

Start Date :

May 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2027

Estimated Enrollment :

174 Patients enrolled

Trial Details

Trial ID

NCT06185608

Start Date

May 22 2025

End Date

October 1 2027

Last Update

May 25 2025

Active Locations (1)

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Ziekenhuis Oost-Limburg

Genk, Limburg, Belgium, 3600

The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks | DecenTrialz