Status:
COMPLETED
MItochondrial Diabetes LOw Carb- Diet Study
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
Stichting Stofwisselkracht
Conditions:
Mitochondrial Diseases
Diabetes-Deafness Syndrome Maternally Transmitted
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In daily practice, doctors and dietitians in the clinic receive many questions in general from patients with a Mitochondrial Disease (MD), and more specific whether nutritional changes can alleviate t...
Detailed Description
Mitochondrial disease (MD) is a clinically and genetically heterogenous group of disorders. The dysfunction of the mitochondrial respiratory chain results in ATP shortage and energy depletion resultin...
Eligibility Criteria
Inclusion
- Mitochondrial disease caused by the m.3243A\>G mutation m.3243A\>G mutation
- BMI ≥ 18.5 kg/m2
- Good cognitive health
Exclusion
- Kidney failure (MDRD \<60 or proteinuria)
- Use of SGLT2-inhibitors
- Already on a carbohydrate restricted diet at baseline (carbohydrate intake \<100 grams per day)
- Pregnancy
Key Trial Info
Start Date :
January 5 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 3 2025
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT06185790
Start Date
January 5 2024
End Date
January 3 2025
Last Update
January 13 2025
Active Locations (1)
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1
Radboudumc
Nijmegen, Gelderland, Netherlands, 6525GA