Status:
RECRUITING
Effect of Gastrectomy on Gut Microbiome and Cognitive Function
Lead Sponsor:
Jiangjiang Bi
Conditions:
Perioperative Neurocognitive Disorders
Gastric Cancer
Eligibility:
All Genders
40-80 years
Brief Summary
Perioperative neurocognitive disorders is a common postoperative complication in elderly surgical patients. The role of gut microbiota in cognitive function has been concerned in recent years. Studies...
Detailed Description
Perioperative neurocognitive disorders is a common postoperative complication in elderly surgical patients, especially in gastrointestinal tumors and cardiac on-pump surgery, and the mechanism is not ...
Eligibility Criteria
Inclusion
- Clinical diagnosis of proximal gastric cancer and will be performed gastrectomy
- American Society of Anesthesiologists (ASA) classification I-III
- Aged 40-80 years
- Perioperative consciousness
Exclusion
- Central nervous system and psychological disorders
- Chronic use of sedatives, antidepressants within the last year
- Parkinson's disease
- Severe immunosuppression
- Severe hearing or vision impairment
- Drug dependence; alcoholism
- Inability to communicate with a physician
Key Trial Info
Start Date :
January 20 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT06186089
Start Date
January 20 2024
End Date
June 1 2026
Last Update
April 11 2024
Active Locations (1)
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1
Tongji Hospital
Wuhan, Hubei, China, 430030