Status:
RECRUITING
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
Lead Sponsor:
Murdoch Childrens Research Institute
Conditions:
Patient-Controlled Analgesia
Eligibility:
All Genders
6-18 years
Phase:
PHASE4
Brief Summary
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patie...
Detailed Description
Morphine and oxycodone are commonly used intravenous (IV) opioids in adult and paediatric post-operative patients. Traditionally, morphine has been preferentially prescribed with PCA. However, IV oxyc...
Eligibility Criteria
Inclusion
- Postoperative patients who are appropriate for a PCA including those aged 6 and above and up to age 18 years.
- Those deemed appropriate for either morphine or oxycodone by their treating anaesthetist.
- American Society of Anaesthesiologists (ASA) score 1-3 inclusive
- Those whose parents or legal guardians have provided informed consent on the patient's behalf.
Exclusion
- Any patients with an allergy, hypersensitivity, or contraindication to morphine or oxycodone.
- Patients in the age group with significant intellectual disability or physical incapacity rendering them incapable of using the PCA device
- ASA score 4 or above
- Inability or unwillingness of parent or legal guardian to provide informed consent for the study.
Key Trial Info
Start Date :
March 13 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 19 2027
Estimated Enrollment :
690 Patients enrolled
Trial Details
Trial ID
NCT06186141
Start Date
March 13 2024
End Date
March 19 2027
Last Update
August 27 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Royal Children's Hospital
Melbourne, Victoria, Australia, 3052