Status:
NOT_YET_RECRUITING
Impact of Skeletal Muscle Quality and Loss on the Outcome of Liver Transplantation
Lead Sponsor:
Zhejiang University
Collaborating Sponsors:
First Affiliated Hospital of Zhejiang University
Shulan (Hangzhou) Hospital
Conditions:
Liver Transplantation
Muscle Loss
Eligibility:
All Genders
Brief Summary
CT imaging-based skeletal muscle assessment has been found to predict the outcomes of many diseases. Previous evidence revealed that pre-transplant muscle quality and post-transplant muscle loss were ...
Eligibility Criteria
Inclusion
- Adult patients undergoing deceased donor liver transplantation (DDLT) for the first time
Exclusion
- Pediatric transplants
- Presence of portal vein tumor thrombus according to imageing before transplantation
- Presence of macrovascular invasion according to imageing before transplantation
- Re-transplants
- Multi-organ transplants
- Patients who died within 30 days after transplantation
- Patients diagnosed with skeletal muscle diseases (e.g. muscle atrophy)
- Patients with serious medical conditions such as heart failure, persistent infection, and renal insufficiency.
Key Trial Info
Start Date :
January 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2029
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT06188273
Start Date
January 1 2024
End Date
January 1 2029
Last Update
January 3 2024
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