Status:

COMPLETED

ImmunoPET Targeting Trophoblast Cell-surface Antigen 2 (Trop-2) in Solid Tumors

Lead Sponsor:

The First Affiliated Hospital of Xiamen University

Conditions:

Tumor

Solid Tumor

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

The objective of the study is to construct a noninvasive approach 68Ga-MY6349 PET/CT to detect the Trop-2 expression of tumor lesions in patients with solid tumors and to identify patients benefiting ...

Detailed Description

As a new trophoblast cell-surface antigen 2 (Trop-2) targeting PET radiotracer, 68Ga-MY6349 is promising as an excellent imaging agent applicable to various cancers. In this research, subjects with va...

Eligibility Criteria

Inclusion

  • adult patients (aged 18 years or older);
  • patients with suspected or newly diagnosed or previously treated malignant tumors (supporting evidence may include MRI, CT, tumor markers and pathology report);
  • patients who had scheduled both standard-of-care imaging (18F-FDG, 68Ga-PSMA, or 68Ga-DOTATATE PET/CT) and 68Ga-MY6349 PET/CT scans;
  • patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion

  • patients with pregnancy;
  • the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Key Trial Info

Start Date :

October 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2024

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06188468

Start Date

October 1 2023

End Date

August 31 2024

Last Update

December 18 2024

Active Locations (1)

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The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China, 361003