Status:
UNKNOWN
Comparison of Aerosol Inhalation and Intravenous Glucocorticoid in the Treatment of Severe AECOPD
Lead Sponsor:
Dong Yang
Collaborating Sponsors:
Jilin University
Conditions:
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Comparison of aerosol inhalation and intravenous glucocorticoid in the treatment of severe AECOPD-------Multicenter, prospective, randomized, controlled clinical study
Detailed Description
This study aims to compare the efficacy and comprehensive benefits of aerosol inhalation and intravenous injection of glucocorticoids in severe AECOPD patients.
Eligibility Criteria
Inclusion
- (1) Patients with AECOPD requiring hospitalization or emergency treatment (COPD acute attacks combined with respiratory failure were eligible). (2) 18 years of age ≤80 years of age (3) Patients and their families are willing to participate in clinical research and sign informed consent.
Exclusion
- Combined with tuberculosis.
- Combined bronchiectasis.
- complicated with definite infectious diseases.
- PCT≥0.5ng/ml or CRP≥30mg/L.
- Serious injury combined with other organ functions
- Contraindications to other glucocorticoid use.
- Concomitant bronchial asthma or positive bronchodilation test
Key Trial Info
Start Date :
October 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06189586
Start Date
October 1 2021
End Date
July 31 2025
Last Update
January 3 2024
Active Locations (1)
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1
The First Hospital of Jilin University
Changchun, Jilin, China, 130021