Status:
UNKNOWN
Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver Failure
Lead Sponsor:
Qilu Hospital of Shandong University
Conditions:
Acute-on-chronic Hepatitis B Liver Failure
Eligibility:
All Genders
16-65 years
Brief Summary
This is a single-center retrospective study. The clinical data of patients with Acute-on-chronic Hepatitis B liver failure who were hospitalized in the Department of Hepatology, Qilu Hospital of Shand...
Detailed Description
The clinical data of patients with Acute-on-chronic Hepatitis B liver failure who were hospitalized in the Department of Hepatology, Qilu Hospital of Shandong University from January 2010 to July 2023...
Eligibility Criteria
Inclusion
- Acute liver function injury TBIL≥5mg/dl(85umol/L) and international normalized ratio (INR) ≥1.5 or PTA≤40% based on previously known chronic hepatitis B or compensated cirrhosis.
- Combined with ascites and/or hepatic encephalopathy within 4 weeks.
- HBsAg（+)\>6 months
Exclusion
- Patients died within 48 hours of admission or withdrew treatment.
- Combined with liver cancer and other extrahepatic organ malignant tumors, rheumatic diseases, hyperthyroidism.
- Age \<18 years old.
Key Trial Info
Start Date :
January 20 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2024
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06190002
Start Date
January 20 2024
End Date
May 31 2024
Last Update
January 5 2024
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