Status:
RECRUITING
Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Zellweger Spectrum Disorder
Eligibility:
All Genders
Brief Summary
The goal of this observational study is to define the course of the retinal degeneration in a ZSD patient cohort. The objective of this study is to gather information so the investigators can: 1. de...
Detailed Description
Participants/guardians will have a 1-hour virtual interview before the first visit to review the tests and determine which tests the participant is able to perform. Below is a list of the vision test...
Eligibility Criteria
Inclusion
- confirmed ZSD with deleterious variants in PEX genes identified
- confirmed or expected retinal involvement
Exclusion
- unable to perform a minimum of one vision test
- severe ZSD disease
Key Trial Info
Start Date :
December 18 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2029
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06190626
Start Date
December 18 2023
End Date
January 1 2029
Last Update
October 7 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Rochester Medical Center/Flaum Eye Institute
Rochester, New York, United States, 14642
2
Eye Institute of Alberta
Edmonton, Alberta, Canada, T5H 3V9
3
Research Institute-McGill University Health Center
Montreal, Quebec, Canada, H4A 3J1