Status:
COMPLETED
Prognostic Significance of CMD Assessed by IMR in HCM Patients
Lead Sponsor:
Ya-Wei Xu
Conditions:
Coronary Cicrovascular Dysfunction
Hypertrophic Cardiomyopathy Patients
Eligibility:
All Genders
18+ years
Brief Summary
The index of microcirculatory resistance (IMR) serves as an indicator of coronary microvascular dysfunction (CMD) with significant prognostic value in various clinical conditions. However, its impact ...
Detailed Description
Patients diagnosed with HCM and referred to the catheterization lab at Shanghai Tenth People's Hospital between 2014 and 2023 for invasive coronary angiography (CAG) due to suspected myocardial ischem...
Eligibility Criteria
Inclusion
- Age \>18 years old;
- echocardiographic evidence of HCM, defined as LV myocardial wall thickness of ≥15 mm and or a LV myocardial wall thickness of ≥13 mm in individuals with a family history of HCM, in the absence of an alternative cause for LV hypertrophy
Exclusion
- significant mitral regurgitation;
- second and third-degree atrioventricular block;
- presence of significant epicardial coronary stenosis (≥50% stenosis) on CAG;
- poor life expectancy resulting from concurrent health disease.;
- reduced contrast opacification (for caIMR assessment)
Key Trial Info
Start Date :
September 13 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2023
Estimated Enrollment :
191 Patients enrolled
Trial Details
Trial ID
NCT06190704
Start Date
September 13 2014
End Date
May 31 2023
Last Update
January 8 2024
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