Status:
RECRUITING
Communication Bridge 3 Study
Lead Sponsor:
University of Chicago
Collaborating Sponsors:
Western University, Canada
National Institute on Aging (NIA)
Conditions:
Primary Progressive Aphasia
Eligibility:
All Genders
18-100 years
Phase:
PHASE2
Brief Summary
This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study i...
Detailed Description
Participants with a diagnosis of PPA and their actively-engaged care partners will be involved in the study for approximately 17 months. Each participant will receive a laptop equipped with the necess...
Eligibility Criteria
Inclusion
- Inclusion Criteria (person with PPA):
- Meets diagnostic criteria for PPA based on neurologist and supporting medical assessments (extracted from medical records)
- English as primary language used in daily communication activities (by self-report)
- Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report)
- Adequate vision (aided or unaided) for reading a newspaper, or other functional materials (by self-report)
- Able to pass technology screening and demonstrates sufficient knowledge for use of video conference and Communication Bridge™ web application use (with or without training)
- Geriatric Depression Scale score ≤ 9
- Mild-moderate PPA informed by a structured interview with a speech-language pathologist and a standardized testing battery.
- Inclusion Criteria (Co-enrolled communication partner):
- 18+ years of age
- English as primary language used in daily communication activities (by self-report)
- Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report)
- Able to pass technology screening\* and demonstrates sufficient knowledge for use of video conference and Communication Bridge™ web application use (with or without training)
- Exclusion Criteria:
- A dementia diagnosis other than Primary Progressive Aphasia
- Participation is co-enrolled in an outside speech language therapy program during the study course.
- Communication partners will be excluded if they have a pre-existing communication impairment that would affect study participation (e.g., aphasia, dementia)
- Medical records will be requested and reviewed to determine eligibility
Exclusion
Key Trial Info
Start Date :
August 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 15 2028
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06191198
Start Date
August 23 2024
End Date
July 15 2028
Last Update
May 30 2025
Active Locations (1)
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1
University of Chicago - American School Building
Chicago, Illinois, United States, 60637