Status:

COMPLETED

Development of a Molecular Diagnostic Tool for Endometrial Cancer.

Lead Sponsor:

MiMARK Diagnostics, S.L.

Collaborating Sponsors:

Hospital Vall d'Hebron

Conditions:

Endometrium Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

WomEC is an in vitro diagnostic test for Endometrial Cancer (EC) based on the detection of the expression level of a combination of 5 proteins in the soluble fraction of a pipelle biopsy specimen. The...

Eligibility Criteria

Inclusion

  • Post-menopausal women (≥1 year without menstruation) with AUB who present with:
  • Endometrium \> 3mm by transvaginal ultrasound, OR
  • Endometrium ≤ 3mm who meet at least one of the following criteria:
  • i. Persistent symptoms (more than one episode of metrorrhagia) ii. Heterogenous endometrium on transvaginal ultrasonography iii. Risk factors (BMI ≥ 30, use of tamoxifen, hormone replacement therapy (HRT), Lynch syndrome, BRCA mutation.
  • Obtaining written informed consent

Exclusion

  • Women with an active pelvic infection.
  • Women who have had viral infections with evidence of active and latent disease such as Hepatitis B, Hepatitis C, and HIV infection. Patients who have had Hepatitis C in the past but who have been successfully treated and in whom viral replication has not been observed in the last year will be included.

Key Trial Info

Start Date :

October 18 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2025

Estimated Enrollment :

1950 Patients enrolled

Trial Details

Trial ID

NCT06192017

Start Date

October 18 2023

End Date

July 31 2025

Last Update

August 28 2025

Active Locations (26)

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Page 1 of 7 (26 locations)

1

Hospital Universitario de Torrevieja

Torrevieja, Alicante, Spain, 03186

2

Hospital Universitari Son Espases

Palma de Mallorca, Balearic Islands, Spain, 07120

3

Hospital Universitari Germans Trias i Pujol

Badalona, Barcelona, Spain, 08916

4

Hospital Dexeus - Quirón de Barcelona

Barcelona, Barcelona, Spain, 08028