Status:

COMPLETED

Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients

Lead Sponsor:

Beijing Friendship Hospital

Conditions:

Anesthesia

Eligibility:

All Genders

65-100 years

Phase:

NA

Brief Summary

This study aims to compare the effects of conscious sedation and intravenous general anesthesia on cardiovascular events in frail patients undergoing digestive endoscopy diagnosis and treatment.

Detailed Description

This study aims to compare the effects of conscious sedation and intravenous general anesthesia on cardiovascular events in frail patients undergoing digestive endoscopy diagnosis and treatment. Both...

Eligibility Criteria

Inclusion

  • Age greater than 65 years old, regardless of gender
  • ASA is classified as Class II and III;
  • BMI 18-28 kg/m2;
  • Patients undergoing examination or treatment outside the operating room;
  • FRAIL scale score ≥ 3 points 6 The patient voluntarily participated in this study and signed an informed consent form.

Exclusion

  • 1 Those who are allergic or contraindicated to drugs such as benzodiazepines, opioids, propofol, and their drug components;
  • 2\. Acute heart failure; Unstable angina pectoris; Myocardial infarction occurred within 6 months prior to screening; Resting electrocardiogram heart rate\<50 beats/minute; Third degree atrioventricular transmission delay; Severe arrhythmia; Moderate to severe heart valve disease;
  • 3\. Patients with severe respiratory diseases (acute respiratory infections, acute exacerbations of chronic obstructive pulmonary disease, uncontrolled asthma, etc.);
  • 4\. Patients who have not received formal antihypertensive treatment or have poor blood pressure control;
  • 5\. Patients with traumatic brain injury, possible presence of intracranial hypertension, cerebral aneurysms, history of cerebrovascular accidents, and central nervous system diseases;
  • 6\. Individuals with mental system diseases (schizophrenia, mania, bipolar disorder, mental disorder, etc.), long-term history of taking psychotropic drugs, and cognitive impairment;
  • 7\. Other situations that have been determined by the researcher to be unsuitable for inclusion.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 12 2024

Estimated Enrollment :

108 Patients enrolled

Trial Details

Trial ID

NCT06192082

Start Date

January 1 2024

End Date

February 12 2024

Last Update

February 20 2024

Active Locations (1)

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1

Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100050