Status:
UNKNOWN
Individual Neuromodulation for PDS
Lead Sponsor:
Ruijin Hospital
Conditions:
Neuromodulation
Parkinsonian Syndromes
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
Parkinsonian Syndromes (PDS) with predominant motor dysfunction include progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and corticobasal degeneration (CBD). Current treatment optio...
Eligibility Criteria
Inclusion
- Compliance with the MDS revised clinical diagnostic criteria for Parkinsonian syndrome (2015 edition)
- aged \>40 years and \<80 years, regardless of gender.
- Patients were relatively stable during the study period and remained stable on medication
- Good compliance, written informed consent, and consent for NIBS long-term intervention treatment
Exclusion
- Patients with severe neuropsychiatric disorders or a previous history of severe neurologic conditions (e.g., epilepsy, cerebrovascular accident, etc.) or traumatic brain injury or brain surgery
- inability to complete the questionnaire independently
- Previous treatment with DBS or SCS; TMS or tDCS within 6 months
- Severe physical illness and any physical condition that can precipitate epilepsy or intracranial hypertension, including cardiovascular and respiratory diseases
- Installation of intracranial stents, pacemakers, coronary stents, cochlear implants, and other human implantable materials
- is currently taking other investigational drugs or is participating in other clinical trials
- Any other condition that the investigator believes makes him or her unsuitable for participation in this study.
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06193278
Start Date
September 1 2023
End Date
June 30 2025
Last Update
January 10 2024
Active Locations (1)
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1
Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200025