Status:
ACTIVE_NOT_RECRUITING
Platelets in Pregnancy
Lead Sponsor:
NYU Langone Health
Conditions:
Hypertensive Disorder of Pregnancy
Eligibility:
FEMALE
18-50 years
Brief Summary
This is a prospective observational cohort study of platelet phenotype in pregnant patients at high-risk for the development preeclampsia. Blood samples will be collected prior to the initiation of da...
Eligibility Criteria
Inclusion
- Inclusion Criteria (Case Group):
- Pregnant patients receiving prenatal care prior to 17 weeks at NYU Langone Health- Obstetrics \& Gynecology Associates
- Age 18-50 years
- Singleton viable gestation
- Pregnant patients at high risk of preeclampsia: Patients meeting USPSTF recommendation for low-dose aspirin (81 mg/day) prophylaxis for preeclampsia based on clinical risk factors (see below)
- Inclusion Criteria (Control Group):
- Pregnant patients receiving prenatal care prior to 17 weeks at NYU Langone Health- Obstetrics \& Gynecology Associates
- Age 18-50 years
- Singleton viable gestation
- Pregnant patients at low risk of preeclampsia: Patients who do not meet USPSTF recommendation for low-dose aspirin (81 mg/day) prophylaxis for preeclampsia based on clinical risk factors.
- Exclusion Criteria (Case and Control Group):
- Allergy to aspirin
- Antithrombotic or antiplatelet therapy
- Anemia (hemoglobin \<10 g/dl) or thrombocytopenia (Platelet count \<100,000), or thrombocytosis (Platelet count \>600)
- Known hemorrhagic diathesis
- Planned delivery outside of NYU
Exclusion
Key Trial Info
Start Date :
January 17 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2026
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT06194643
Start Date
January 17 2023
End Date
March 1 2026
Last Update
September 18 2025
Active Locations (1)
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1
NYU Langone Health
New York, New York, United States, 10016