Status:

RECRUITING

Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer

Lead Sponsor:

IRCCS San Raffaele

Conditions:

Clear Cell Renal Cell Carcinoma

VHL Syndrome

Eligibility:

All Genders

18-99 years

Brief Summary

The goal of this study is to comprehensively map intra and inter tumor heterogeneity of ccRCC in VHL patients through the use of imaging, molecular biology and genomics techniques.

Detailed Description

It was hypothesized that the high intra- inter-tumor heterogeneity of sporadic ccRCC also defines VHL-ccRCCs, including different lesions within individual patients, and it was assumed that decoding V...

Eligibility Criteria

Inclusion

  • VHL syndrome
  • Presence of at least 3 kidney tumors larger that 3cm to be surgically removed

Exclusion

  • Absence of VHL
  • Quantity of kidney tumors \< 3
  • Absence of surgery performance

Key Trial Info

Start Date :

November 8 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2025

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT06195150

Start Date

November 8 2023

End Date

October 31 2025

Last Update

May 1 2025

Active Locations (1)

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1

IRCCS Ospedale San Raffaele

Milan, MI, Italy, 20132