Status:
WITHDRAWN
The Use of OTSC in LBGDU to Standard Endoscopic Hemostatic Methods
Lead Sponsor:
Chinese University of Hong Kong
Collaborating Sponsors:
King Chulalongkorn Memorial Hospital
West China Hospital
Conditions:
Bleeding Peptic Ulcer
Eligibility:
All Genders
18-111 years
Phase:
NA
Brief Summary
In managing bleeding gastroduodenal ulcers, endoscopic control of bleeding is the first line treatment-further bleeding after endoscopic hemostasis is associated with a 3-fold increase in mortality. L...
Detailed Description
Endoscopic hemostatic treatment is the cornerstone of the management of patients with acute nonvariceal upper gastrointestinal bleeding. The current standard in endoscopic hemostasis includes the use ...
Eligibility Criteria
Inclusion
- patients admitted with acute upper gastrointestinal bleeding (melena, hematemesis, or decrease in hemoglobin level with or without hypotension).
- large gastro-duodenal ulcers (20 mm in size or more)
- active bleeding (pulsatile or Forrest Ia bleeding, oozing from a visible vessel, or Forrest Ib bleeding) or a nonbleeding visible vessel (Forrest IIa lesion). Clots overlying bleeding lesions are injected with diluted epinephrine and then irrigated or elevated using a cheese-wiring technique. If a vessel is then unveiled, we can proceed with randomization.
Exclusion
- patients with esophagogastric varices
- pregnant or lactating women
- patients who cannot provide written consent
- moribund from their co-morbid illnesses and are not considered for active treatment.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2027
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT06196710
Start Date
October 1 2025
End Date
December 1 2027
Last Update
January 24 2025
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