Status:

WITHDRAWN

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

Lead Sponsor:

Ugur Arzu Kulu

Conditions:

Acute Myeloid Leukemia, Adult

Graft Versus Host Disease

Eligibility:

All Genders

18+ years

Brief Summary

The investigators aimed to reveal the relationship between serum markers of pyroptosis, GVHD biomarkers and endothelial damage markers in patients who were planned for allogeneic stem cell transplanta...

Detailed Description

In the study, in patients who were planned to receive allogeneic stem cell transplantation for AML, pre-transplant period (before and after central catheter insertion) and post-transplant period (+1, ...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • Patients with acute myeloid leukemia undergoing allogeneic bone marrow transplantation
  • Patients followed up by the Department of Hematology, Ankara University Faculty of Medicine Hospitals

Exclusion

  • Patients under 18 years of age
  • Patients with non-AML transplant indication
  • Patients not followed up by the Department of Hematology, Ankara University Faculty of Medicine Hospitals

Key Trial Info

Start Date :

November 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 15 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT06200441

Start Date

November 15 2023

End Date

November 15 2024

Last Update

January 29 2025

Active Locations (1)

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1

Ankara University, Department of Hematology

Ankara, Turkey (Türkiye), 06000