Status:
UNKNOWN
Neurofilament Light Chain in Amyotrophic Lateral Sclerosis
Lead Sponsor:
Charite University, Berlin, Germany
Collaborating Sponsors:
Boris Canessa ALS Stiftung
Conditions:
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Eligibility:
All Genders
18+ years
Brief Summary
This study assesses the performance of serum neurofilament light chain (sNfL) in amyotrophic lateral sclerosis (ALS) in a wide range of disease courses, in terms of ALS progression, disease duration, ...
Detailed Description
The aim of this study is to investigate the correlation between the NfL serum concentration and the natural course of the disease, the ALS progression rate as measured by the ALS functional rating sca...
Eligibility Criteria
Inclusion
- Diagnosis of amyotrophic lateral sclerosis including specific forms
- Patient's informed consent to participate in this study
- Minimum age of 18 years
- Willingness for blood collection
Exclusion
- Unwillingness to store and share pseudonymized medical data collected in the study
- Evaluation by the investigator, which excludes participation
Key Trial Info
Start Date :
November 11 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT06201650
Start Date
November 11 2020
End Date
December 31 2024
Last Update
January 11 2024
Active Locations (19)
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1
Medizinische Universität Innsbruck
Innsbruck, Austria, 6020
2
Vivantes Klinikum Kaulsdorf
Berlin, Germany, 12621
3
Charité Universitätsmedizin Berlin
Berlin, Germany, 13353
4
Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH
Bochum, Germany, 44789