Status:

RECRUITING

Clinical Study of CLDN18.2 PET/CT for Noninvasive Diagnosis of Gastric and Pancreatic Cancer

Lead Sponsor:

YiHui Guan

Conditions:

Positron Emission Tomography

Pancreatic Neoplasms

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

In this study, we will investigate the diagnostic efficacy and safety of \[18F\]F-H3RESCA-3A12 and \[68Ga\]Ga-NOTA-3A12 in metastatic gastric and pancreatic cancers, and evaluate the sensitivity and s...

Eligibility Criteria

Inclusion

  • (1) Age between 18 and 65 years old, gender is not limited. (2) Patients with gastric or pancreatic cancer confirmed by puncture or surgical pathology.
  • (3) Written informed consent signed by the subject or his/her legal guardian or caregiver.
  • (4) Willingness and ability to cooperate with all programs of this study.

Exclusion

  • \- (1) Severe hepatic or renal insufficiency; (2) Targeted therapy before radiotherapy or PET/CT scan. (3)Renal function: serum creatinine less than or equal to the upper limit of the normal range;Liver function: bilirubin, AST(SGOT)/ALT(SGPT) less than or equal to the upper limit of the normal range.
  • (4) History of serious surgery in the last month. (5) Those who have participated in other clinical trials during the same period.

Key Trial Info

Start Date :

December 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06203613

Start Date

December 1 2023

End Date

December 1 2024

Last Update

February 16 2024

Active Locations (1)

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1

PET Center, Huashan Hospital, Fudan University

Shanghai, China, 200235