Status:
RECRUITING
Evaluation of Regenerative Potential in Horizontal Bone Loss Using VCMX Along With LASER Therapy
Lead Sponsor:
Postgraduate Institute of Dental Sciences Rohtak
Conditions:
Bone Loss, Alveolar
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Background- Periodontitis, an inflammatory disease of the periodontium, is one of the major causes of tooth mortality. Of all the bone destruction patterns that are present in periodontitis, horizonta...
Detailed Description
Periodontitis is a chronic inflammatory disease triggered by gram-negative anaerobic microbes and involves chronic inflammation that causes the destruction of the tooth-supporting apparatus and can le...
Eligibility Criteria
Inclusion
- Periodontitis stage 2 and stage 3 patients will be enrolled according to criteria of 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
- Horizontal bone loss defects with depth ≥ 5 mm (initially analyzed by trans-gingival probing and intraoral periapical radiographs and will be confirmed further after flap elevation and CBCT)
- PPD ≥ 5 mm
- CAL ≥ 3 mm
- Tooth mobility \< grade 1
- Experimental teeth and adjacent teeth would be required to be vital and free of caries or dental restorations
Exclusion
- Any systemic illness that could affect the periodontium or outcome of periodontal therapy
- patients on medications such as corticosteroids or calcium channel blockers
- long-term nonsteroidal anti-inflammatory drug therapy
- pregnant or lactating women
- current and past smoker
- Periodontitis stage 4
- teeth with one-wall defect, the presence of exostoses and ledges, grade II and grade III mobile teeth, defects extending to a root furcation area, unrestorable teeth, fractured/perforated roots, developing permanent teeth, endodontically treated teeth, and teeth with premature contact and dental prosthesis.
Key Trial Info
Start Date :
April 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06204588
Start Date
April 1 2024
End Date
March 1 2025
Last Update
May 17 2024
Active Locations (1)
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1
Post Graduate Institute of Dental Sciences
Rohtak, Haryana, India, 124001