Status:

RECRUITING

Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid )

Lead Sponsor:

Neurosoft Bioelectronics SA

Collaborating Sponsors:

UMC Utrecht

European Research Council

Conditions:

Focal Epilepsy

Intraoperative Monitoring

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objective of this prospective interventional monocentric clinical investigation is to evaluate the feasibility and performance of the flexible high-density SOFT ECoG electrode grids, manufactured ...

Eligibility Criteria

Inclusion

  • Age ≥18 years at the time of enrolment
  • Lesional epilepsy (incl. secondary mesial temporal sclerosis) that is considered a candidate for intra-operative high-density grid recordings (incl. patients who underwent sEEG preceding resective surgery)
  • Provided informed consent for study participation by the subject

Exclusion

  • Occipital lesion
  • Surgeries involving a primary mesial temporal lesion, a disconnection, or hemispherectomy.
  • Planned ioECoG recordings during fully awake surgery and/or functional recordings
  • Use of anticoagulants that cannot be discontinued during the perioperative period, or a factor XIII deficiency or any other haematological disease
  • Active participation in another investigational device study
  • Any other condition that in the opinion of the investigator may adversely affect the safety of the subject or would limit the subject's ability to complete the study.
  • Insufficient understanding of Dutch language.

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2027

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT06205160

Start Date

January 1 2025

End Date

March 1 2027

Last Update

December 10 2025

Active Locations (1)

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1

University Medical Center (UMC) Utrecht

Utrecht, Netherlands, 3584CX