Status:

RECRUITING

Diaphragm Structure and Function in Childhood Cancer Survivors

Lead Sponsor:

University of Maryland, Baltimore

Conditions:

Childhood Cancer

Cancer Survivors

Eligibility:

All Genders

6-12 years

Phase:

NA

Brief Summary

The purpose of this research is to study the feasibility of a specific training program for the breathing muscles (inspiratory muscle training) and the effects on how breathing is regulated during exe...

Detailed Description

During the first study visit, participants will undergo a series of pulmonary function and muscle performance tests followed by treadmill walking trials at different speeds with concurrent expired gas...

Eligibility Criteria

Inclusion

  • Completed medical treatment (chemotherapy, chemotherapy/surgery, chemotherapy/radiation or any combination of cancer treatment) for any type of cancer, except for cancer of the central nervous system, at least 1 year ago

Exclusion

  • History of neuromuscular, cardiac, or pulmonary disease prior to the diagnosis of cancer
  • Recent injury or condition (less than 6 months ago) that precludes strength testing or walking
  • Dyspnea with minimal activity (4 on the modified Medical Research Council Dyspnea Scale)

Key Trial Info

Start Date :

March 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT06205251

Start Date

March 15 2024

End Date

December 1 2025

Last Update

July 2 2025

Active Locations (1)

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University of Maryland, Baltimore

Baltimore, Maryland, United States, 21201