Status:
COMPLETED
Predictors of Residual Tumor at Second Transurethral Resection for pT1 Non-muscle Invasive Bladder Cancer
Lead Sponsor:
University of Trieste
Conditions:
Bladder Cancer
Non Muscle Invasive Bladder Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The START study is a multicentre retrospective project. The aim is to identify clinico-pathological predictors of residual tumor at time of second transurethral resection of bladder tumor (re-TURBt) a...
Detailed Description
Background Transurethral resection of bladder tumor (TURBt) is the standard procedure for bladder cancer (BCa) diagnosis and represents, at the same time, the most important therapeutic moment for pa...
Eligibility Criteria
Inclusion
- patients undergoing second TURBt (re-TURBt) for pT1LG/HG NMIBC after a macroscopically completed first TURBt (in patients with multiple lesions only the index lesion pT1 conditioning the indication of re-TURBt will be considered). Therefore, presence of residual tumor or not at time of re-TURBt will be assessed at site of previous pT1.
- patients able to provide written informed consent;
- clinical-localized non-metastatic disease (cN0, cM0).
Exclusion
- patients with clinical non-localized BCa (cN+, cM+);
- patients with incomplete resection at time of first TURBt according to surgeon: macroscopic evidence of residual tumor, too long resection requiring a second-look will be excluded from the current study;
- patients with incomplete clinical or demographic or pathological data;
- patients who were unable to provide written informed consent;
- patients who underwent urgency or emergency procedures in life-threating scenario
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
1300 Patients enrolled
Trial Details
Trial ID
NCT06205277
Start Date
January 1 2022
End Date
December 31 2023
Last Update
January 12 2024
Active Locations (1)
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1
University of Trieste - Azienda Ospedaliera Universitaria Giuliano Isontina
Trieste, Friuli Venezia Giulia, Italy, 34149