Status:
RECRUITING
Microbiome and Diet in Parkinson's Disease
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Weston Family Foundation
Conditions:
Parkinson Disease
Diet, Healthy
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
The goal of this pilot study is to examine the feasibility and effects of an 18-month intervention diet compared to an active control diet (standard diet) in those living with Parkinson's Disease (PD)...
Detailed Description
Those meeting general eligibility criteria and are agreeable, will come to the University of British Columbia (UBC) for an onsite Screening visit to sign the consent form, review eligibility, and comp...
Eligibility Criteria
Inclusion
- Eligible if the person living with Parkinson's has/is:
- a clinical diagnosis of PD,
- cognitively stable (no clinical dementia),
- between 40-80 years old,
- able to travel to UBC for 6 onsite visits over 18 months,
- sufficient English proficiency (coaching and cooking classes are in English only),
- on a stable dopaminergic medication for at least one month before baseline,
- computer and internet access at home, and can be available via video link for at least 80% of the study sessions.
Exclusion
- Not eligible, if person has/is:
- a diagnosis of atypical parkinsonism,
- medical or psychiatric conditions that would prevent full participation in the nutrition intervention (such as food allergies), significant dysphagia, diabetes on insulin, anti-coagulation on warfarin, and inflammatory bowel disease,
- clinical dementia,
- unable to complete questionnaires or understand study instructions,
- using of immunomodulatory agents,
- used Probiotics in the last 4 weeks prior to study start,
- used Antibiotics in the last 3 months prior to study start,
- contraindications for MRI.
Key Trial Info
Start Date :
December 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06207136
Start Date
December 3 2024
End Date
December 31 2027
Last Update
February 21 2025
Active Locations (1)
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1
UBC Pacific Parkinson's Research Centre
Vancouver, British Columbia, Canada, V6T 2B5