Status:
RECRUITING
Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease
Lead Sponsor:
University of Alabama at Birmingham
Conditions:
Kidney Stone
Eligibility:
All Genders
19-89 years
Phase:
NA
Brief Summary
The true capacity for a healthy diet to improve urinary stone risk factors is not well-defined. The objective of this study is to measure the effect of adopting a healthy dietary pattern on kidney sto...
Eligibility Criteria
Inclusion
- Birmingham, AL area participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study OR patients of the University of Alabama at Birmingham/Kirklin Clinic
- Self-reported, documented, and/or prior imaging-based diagnosis of kidney stone disease
- Age 19-89
- Any sex
- Any race
- Able to provide informed consent
- Willing to perform 24-hour urine collections
- Willing to consume meals prepared by Bionutrition Unit
- No food allergies/intolerance to any of the foods in the study menus
- Willing to stop for 7 days before and during study: Multivitamins and/or Dietary supplements (including calcium and vitamin C)
Exclusion
- Dialysis
- Kidney transplant recipient
- Estimated glomerular filtration rate (eGFR) \<60 ml/min/1.73m2 based on historical laboratory measurements
- Renal tubular acidosis
- Current use of acetazolamide, topiramate, or zonisamide
- Primary hyperparathyroidism or history of parathyroidectomy
- Hyperthyroidism
- Sarcoidosis
- Primary hyperoxaluria
- Cystinuria
- Nephrotic syndrome
- Malabsorptive conditions including inflammatory bowel disease or history of malabsorptive surgery (e.g., Roux-en-Y gastric bypass, small bowel resection)
- Urinary retention requiring catheterization
- Urinary diversion
- Pregnancy
- Breastfeeding
- Malignancy treated in the past 12 months other than non-melanoma skin cancer
Key Trial Info
Start Date :
January 6 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2027
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06210009
Start Date
January 6 2025
End Date
August 31 2027
Last Update
January 15 2025
Active Locations (1)
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1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294