Status:
NOT_YET_RECRUITING
Compared Unidirectional Valve Apparatus and Occluding the Non-ventilated Endobronchial Lumen for Lung Collapse.
Lead Sponsor:
Sichuan University
Conditions:
Video-assisted Thoracoscopic Surgery
One-Lung Ventilation
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
With the rapid advancement of thoracoscopic surgery in recent years, surgeons have set higher standards for the quality of non-ventilated lung collapse. In a prior investigation, we examined a unidire...
Detailed Description
In this study, patients who meet the enrollment criteria will be randomized 1:1 to the unidirectional valve group or the closed lumen group. After patients entered the operating room, their heart rat...
Eligibility Criteria
Inclusion
- Age: 18-75 years old
- American Society of Anesthesiologists (ASA) physical status I to III
- Patients scheduled to undergo video-associated thoracoscopic surgery requiring one-lung ventilation
Exclusion
- A - pre-operative
- anticipated difficult intubation
- New York Heart Association (NYHA) heart failure class III/IV
- body mass index≥35kg/m2
- patients with abnormal expiratory recoil \[forced expiratory volume in 1s (FEV1) less than 70% of predicted values
- chronic obstructive pulmonary disease (COPD) or severe asthma
- prior thoracic surgery or radiotherapy
- a history of pleural or interstitial disease
- B - post-randomization
- the discovery of pleural adhesions following pleural opening
- a delay of more than 25 minutes between the onset of one-lung ventilation and chest opening
- the duration between the onset of one-lung ventilation and chest opening less than 10 minutes
- a switch to thoracotomy as the type of surgical procedure
- he occurrence of significant adverse events during the operation, such as severe bleeding (more than 1500ml), fatal arrhythmia, respiratory arrest, or cardiac arrest
Key Trial Info
Start Date :
January 25 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 25 2024
Estimated Enrollment :
192 Patients enrolled
Trial Details
Trial ID
NCT06210256
Start Date
January 25 2024
End Date
June 25 2024
Last Update
January 18 2024
Active Locations (1)
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1
West China Hospital
Chengdu, Sichuan, China, 610041