Status:

ACTIVE_NOT_RECRUITING

The ACES Study for Aseptic Pleural Effusion

Lead Sponsor:

Pleural Dynamics, Inc.

Collaborating Sponsors:

Medical Metrics Diagnostics, Inc

Conditions:

Pleural Effusion

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The study will enroll recurrent aseptic pleural effusion patients who are designated by their physician as needing treatment to control the fluid. Baseline assessment will include a history and physic...

Detailed Description

Pleural Dynamics is the first company to provide a fully implantable automatic effusion shunt that is powered by normal breathing and is designed for continuous symptom relief, and does not require an...

Eligibility Criteria

Inclusion

  • Recurrent pleural effusion after thoracentesis for which the physician has determined that a catheter implantation is indicated.
  • Symptoms of PE such as shortness of breath, cough, or chest fullness/chest discomfort based on patient report to physician.
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-3.
  • Patient is willing and able to meet all study requirements, including follow-up visits and receiving study related telephone calls.

Exclusion

  • Recurrent pleural effusion after thoracentesis for which the physician has determined that a catheter implantation is indicated.
  • Symptoms of PE such as shortness of breath, cough, or chest fullness/chest discomfort based on patient report to physician.
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-3.
  • Patient is willing and able to meet all study requirements, including follow-up visits and receiving study related telephone calls.

Key Trial Info

Start Date :

May 12 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT06210685

Start Date

May 12 2024

End Date

December 1 2025

Last Update

August 11 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Memorial Healthcare System

Hollywood, Florida, United States, 33021

2

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21224

3

University of North Carolina Pulmonary and Critical Care Medicine

Chapel Hill, North Carolina, United States, 27599

4

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232