Status:
COMPLETED
Single- Vs. Triple-Injection Techniques for Intertransverse Process Blocks in Video-Assisted Thoracoscopic Surgery: a Randomized Trial on Sensory Blockade
Lead Sponsor:
Chiang Mai University
Conditions:
Intertransverse Process Block
Video Assisted Thoracic Surgery
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
The intertransverse process block (ITPB) is an alternatives technique of regional anesthesia for thoracic surgery. However, the precise technique of ITPB remains developing. This study aims to evaluat...
Detailed Description
Objectives: evaluate the efficacy of single and triple injections of ultrasound-guided ITPB in adult patients undergoing video-assisted thoracoscopic surgery for pulmonary resection Setting: Single ce...
Eligibility Criteria
Inclusion
- Patients aged 20-70 years old
- Undergoing scheduled the first time for each side of video-assisted thoracoscopic surgery (VATS) for pulmonary resection
- American Society of Anesthesia (ASA) physical status I-III
- Patients have ability to communicate and understand the study and accept to participate in study
- Body weight \>40 kg
Exclusion
- Patients who allergic to bupivacaine, lidocaine, NSAIDS, paracetamol, and dexamethasone
- Patients who have following underlying disease: renal impairment (diagnosed of end-stage renal disease (ESRD) or chronic kidney disease (CKD) which estimated glomerular filtration rate (eGFR) \< 60 ml/min per 1.73 square meters) , hepatic impairment (diagnosed of cirrhosis or evidence of abnormal liver function test which are increased liver enzymes or bilirubin level), coagulopathy (diagnosed of disease associated with abnormal coagulation, currently use any anticoagulants or evidence of prolong prothrombin time (PT) or partial thromboplastin time (PTT)), thrombocytopenia (platelet count less than 150,000/microliter), platelet disfunction from any causes such as current use antiplatelet or uremia (BUN level \> 60 mg/dL) , morbid obesity (BMI \>40 kg/m2), pre-existing neurological deficits, chronic pain (diagnosed of chronic pain disease or current use regular analgesic drugs), or any drug addiction • Withdrawal criteria: a participant will be withdrawn from the study in case of
- 1\. Procedural failure: the operator cannot place the needle tip in the intertransverse tissue according to the technical difficulty or abnormal anatomy after 15 minutes of performing the block (from the beginning of needle insertion to the injection of local anesthetic) 2. Anesthetic related events including cardiac arrest, difficult intubation 3. Surgical related events including massive bleeding, major organ injury, converted operation to open thoracotomy and reoperation within admission 4. Participant related reasons including patient's willing to withdraw from the study or failure to adhere adequately to protocol requirements such as premature discharge. However, the withdrawn participant will be continued follow up of clinical outcome.
Key Trial Info
Start Date :
January 25 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06210958
Start Date
January 25 2024
End Date
November 1 2024
Last Update
February 19 2025
Active Locations (1)
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1
Department of Anesthesiology
Chiang Mai, Chiang Mai, Thailand, 50200