Status:
COMPLETED
Cardiovascular And Metabolic Risk After Arthroplasty
Lead Sponsor:
University of Tartu
Collaborating Sponsors:
Tartu University Hospital
Estonian Science Foundation
Conditions:
Osteoarthritis of the Knee
Osteoarthritis of the Hip
Eligibility:
All Genders
Brief Summary
Osteoarthritis is a chronic joint disease that lacks curative therapy. Epidemiological studies show increase in the burden of disease. Total joint arthroplasty is one of the best treatment options for...
Eligibility Criteria
Inclusion
- Inclusion Criteria for the arthroplasty group:
- primary hip and knee OA (according to the American College of Rheumatology criteria) eligible for total joint arthroplasty
- Exclusion Criteria for the arthroplasty group:
- posttraumatic OA, infectious and endocrine related arthropathy, any acute or chronic inflammatory disease, malignancy, renal insufficiency (estimated glomerular filtration rate (eGFR) \< 60ml/min/1.73m2), cardiac arrhythmia, clinically significant heart failure, valvular disease, diabetes.
- Exclusion criteria for the control group:
- any concomitant acute or chronic inflammatory disease, a visit to family practitioner due to hip or knee joint complaints, any persistent knee or hip joint pain, diabetes, symptomatic coronary artery disease, cardiac arrhythmia, cerebrovascular or peripheral artery disease, malignancies and renal insufficiency.
Exclusion
Key Trial Info
Start Date :
March 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2023
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT06211465
Start Date
March 1 2014
End Date
April 1 2023
Last Update
January 18 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Tartu
Tartu, Tartu, Estonia, 51014