Status:
COMPLETED
Dyspnea and Cerebral Cortex Activation Measured by fNIRS During Spontaneous Breathing Trial
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Dyspnea
Eligibility:
All Genders
18+ years
Brief Summary
Background: In Intensive Care Unit (ICU) patients, dyspnea is frequent, severe and exerts unfavorable effects on the short, medium and long term. Detection and quantification rely on the patient's sel...
Detailed Description
Patient management will not be altered by the study. Patients will be included if the clinician in charge of the patient has decided to perform a SBT on the patient. SBT conditions will be those of cu...
Eligibility Criteria
Inclusion
- Invasive mechanical ventilation \> 24h
- Ability to realize a spontaneous breathing trial, defined by the following criteria: Effective cough, no excessive tracheo-bronchial secretions, resolution of the disease that prompted the intubation, heart rate ≤ 140/min, pressure systolic blood pressure between 90 and 160 mmHg, no or very low dose of amines, SpO2 \> 90% in 40% FiO2 (or PaO2/FiO2 \> 150), positive expiratory pressure \< 8 cmH2O, respiratory rate ≤ 35/min, tidal volume \> 5ml/kg of theoretical body weight, respiratory rate / tidal volume ratio \< 105 cycles/min/L
- Decision by the clinician in charge of the patient to perform a SBT,
- Patient or relative consent obtained.
Exclusion
- Minor patient,
- Pregnant or breastfeeding woman
- Agitation/sedation: RASS ( Richmond Agitation-Sedation Scale) \> 2 or \< 2,
- Person under legal protection (guardianship, curators), safeguarded by justice.
Key Trial Info
Start Date :
May 3 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 4 2024
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT06211738
Start Date
May 3 2024
End Date
November 4 2024
Last Update
July 28 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Service de Médecine Intensive Réanimation du département R3S, hôpital Pitié salpêtrière
Paris, France, 75013