Status:

COMPLETED

Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula

Lead Sponsor:

University of Malaya

Conditions:

Fistula in Ano

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This is a prospective, double-blinded randomised controlled trial conducted at two tertiary hospitals by a credentialed colorectal surgeon.

Detailed Description

Patients with high transphincteric fistulas were blinded and randomized to either laser or ligation of the fistula tract (LIFT). Pain scores at rest and movement, at 6 and 24 hours post operatively we...

Eligibility Criteria

Inclusion

  • Complex transphincteric fistulas:
  • high transphincteric fistula, involving more than 30% of the external anal sphincter
  • Multiple fistulas
  • Anterior fistulas
  • 18-75 years old
  • Able to give consent
  • New or recurrent fistulas
  • Fistulas with or without setons

Exclusion

  • Active perianal sepsis requiring drainage
  • Fistulas of non-cryptogladular origin- Crohn's, TB, malignancy
  • Expected lifespan less than 6 months
  • Pregnant women
  • Patients with more than 1 definitive surgery done for the fistula before
  • Patients with human immunodeficiency virus infection
  • Patients with pre-existing chronic pain disorders
  • Patients with Non-steroidal Anti-inflammatory Drug (NSAIDS) / Paracetamol allergies

Key Trial Info

Start Date :

January 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 2 2021

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT06212739

Start Date

January 1 2018

End Date

August 2 2021

Last Update

January 19 2024

Active Locations (1)

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University Malaya Medical Centre

Kuala Lumpur, Kuala Lumpur, Malaysia, 59100