Status:

UNKNOWN

A Study of Remimazolam Tosilate for Sedation in Non-intubated Diagnostic and Therapeutic Procedures

Lead Sponsor:

Jiangsu HengRui Medicine Co., Ltd.

Conditions:

Sedation in Non-intubated Diagnostic and Therapeutic Procedures

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of Remimazolam Tosilate for Injection for sedation in non-intubated diagnostic and therapeutic procedures

Eligibility Criteria

Inclusion

  • Age ≥18 years old, male or female
  • Intending to undergo routine gastroscopy or colonoscopy
  • ASA (American Society of Anesthesiologists) I to III
  • 18 kg/m2≤BMI (Body Mass Index)≤30kg/m2
  • Signed informed consent

Exclusion

  • Subjects need to be tracheal intubation
  • Subjects need to be complicated endoscopic diagnostic and therapeutic procedures
  • Subjects who have had severe cardiovascular diseases or severe arrhythmias within 6 months prior to signing the ICF
  • Heart rate \<50 beats/min during the screening period
  • Poor blood pressure control during the screening period
  • Subjects with severe respiratory diseases
  • Subjects with respiratory management difficulties (Modified Mallampati grade IV)
  • Subjects with a history of mental illness (schizophrenia, mania, bipolar disorder, psychosis, etc.), long-term use of psychotropic drugs, and cognitive impairment
  • A history of drug abuse or addiction within 2 years prior to signing the ICF
  • Pregnant women or those in lactation period
  • Allergic to relevant drugs ingredient or component in the study
  • Currently participating in or planning to participate in other drug or device clinical trials during this study
  • Other conditions deemed unsuitable to be included

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2024

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT06216444

Start Date

January 1 2024

End Date

March 1 2024

Last Update

January 22 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China, 200032