Status:
NOT_YET_RECRUITING
PRE- MISTIC: MRI and Cine Imaging to Improve Staging of Tumors in the Colon
Lead Sponsor:
Radboud University Medical Center
Conditions:
Colon Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
At this moment, we use CT and endoscopy to clinically stage colon tumours. Unfortunately, the combination of these imaging techniques is highly inaccurate. 40% of advanced pathological colon tumours (...
Eligibility Criteria
Inclusion
- Patients with clinical suspicion for T3 or T4 tumor based on standard clinical work-up with endoscopy and CT-scan
- Age \> 18 years
- WHO Performance status of 0-2
Exclusion
- Patients with contraindications for MRI
- Patients with clinical contraindications to undergo colon surgery
- Patients receiving neoadjuvant therapy prior to surgery
- Patients with known allergy to iodine or gadolinium contrast
- Patient with contra-indication for contrasts based on kidney failure Neoadjuvant therapy is currently not the standard of care for advanced colon carcinoma, and applied only in selected cases or as part of a clinical trial. Because neoadjuvant therapy could result in tumor regression, thus impacting the gold standard of histological examination, patients selected for neoadjuvant therapy are excluded from this study.
Key Trial Info
Start Date :
January 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT06216743
Start Date
January 1 2025
End Date
December 31 2025
Last Update
December 31 2024
Active Locations (1)
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1
Radboud University Nijmegen Medical Center
Nijmegen, Gelderland, Netherlands, 6500HB