Status:
COMPLETED
Mechanistic Effect of Ketones on Cerebral Blood Flow
Lead Sponsor:
McMaster University
Conditions:
Cerebrovascular Function
Cerebral Blood Flow
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
Oral supplements containing exogenous ketones have recently become available and represent a novel tool for increasing plasma ketone bodies without the need for dietary restriction. Early evidence sug...
Eligibility Criteria
Inclusion
- Having a normal blood pressure (≤125/≤85 mmHg)
- Between the ages of 18 and 35
Exclusion
- Individuals who are obese (body mass index \> 30 kg/m\^2)
- Individuals who smoke
- Individuals with respiratory illnesses
- A history of type 2 diabetes, hypoglycemia, or cardiovascular diseases (i.e. heart attack, stroke)
- Individuals currently following a ketogenic diet or taking ketone supplements
- Individuals with a history of concussion(s) with persistent symptoms
- Individuals participating in elite-level physical training (i.e. varsity athletics)
Key Trial Info
Start Date :
January 19 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2024
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT06217159
Start Date
January 19 2024
End Date
August 31 2024
Last Update
April 23 2025
Active Locations (1)
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1
McMaster University
Hamilton, Ontario, Canada, L8S 4K1