Status:
RECRUITING
The Effect of GLP-1 Agonist in Patients With Hypothalamic Obesity: Prospective, Pilot Study
Lead Sponsor:
Seoul National University Hospital
Conditions:
Panhypopituitarism
Craniopharyngioma
Eligibility:
All Genders
19+ years
Phase:
EARLY_PHASE1
Brief Summary
GLP-1 analogs are used as agents in the existing treatment of obesity. However, there are lack of previous reports on the effectiveness and role of GLP-1 analogs in the development of obesity traits i...
Detailed Description
Study Overview * Collecting baseline clinical information, comorbidities, pituitary hormone status assessment, and treatment options, including supplemental therapies and surgery. * Assessment of fac...
Eligibility Criteria
Inclusion
- Patients diagnosed with a hypothalamic tumor and treated surgically with confirmed hypothalamic damage
- 19 years of age or older
- Have a body mass index of at least 27 and less than 30 (27≤BMI\<30) and one or more confirmed weight-related medical conditions, or a body mass index of 30 or greater (BMI≥30).
- Voluntarily agreed to participate in the study after receiving a full explanation of the study.
Exclusion
- Unable to fully understand the instructions for participation in the study or unable to give voluntary consent.
- Presence or history of a medical condition or disease that, in the opinion of the investigator, would make it difficult for the patient to participate fully for the duration of the study or to interpret the results of the study
- Taking medications that may affect weight, except for hormone replacement therapy, in the last 6 months
- non-primary tumor patient
- Diagnosis of severe renal dysfunction, liver dysfunction, or thyroid disease among other underlying conditions
Key Trial Info
Start Date :
November 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 8 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06217848
Start Date
November 28 2022
End Date
March 8 2024
Last Update
January 23 2024
Active Locations (1)
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1
Seoul National University Hospital
Seoul, Jongno-gu, South Korea, 03080