Status:

COMPLETED

A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer

Lead Sponsor:

Renmin Hospital of Wuhan University

Conditions:

Esophageal Cancer

Eligibility:

All Genders

18-75 years

Brief Summary

This study is a retrospective study of clinical specimens. The study subjects were patients with esophageal cancer who received immunotherapy. Tumor tissue specimens surgically removed from patients b...

Eligibility Criteria

Inclusion

  • Esophageal cancer patients receiving immunotherapy
  • Radical esophagectomy for esophageal cancer at our institution prior to receiving immunotherapy
  • Age greater than or equal to 18 years and less than or equal to 75 years old Imaging to assess patient efficacy after cycle 2 immunotherapy (CR/PR, SD/PD according to recist 1.1)
  • Pathology Tumor tissue available

Exclusion

  • Clinical and pathologic information not available
  • Combined history of other malignant tumors
  • Unavailability of surgically resected tissue
  • Preoperative neoadjuvant therapy
  • Radical esophagectomy for esophageal cancer not performed prior to immunotherapy

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2024

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT06219031

Start Date

December 1 2023

End Date

January 1 2024

Last Update

January 26 2024

Active Locations (1)

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Renmin hosptial of Wuhan University

Wuhan, Hubei, China, 430060