Status:

COMPLETED

Comparison of the Effects of Dexmedetomidine and Ketamine Infusion on the Inflammatory Response in Liver Resection

Lead Sponsor:

Ataturk University

Conditions:

Inflammation

Analgesia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Resection is being performed with increasing frequency in the treatment of surgical diseases of the liver. Ischemia-reperfusion injury is a major cause of liver injury occurring during surgical proced...

Detailed Description

General anesthesia will apply to all patients. Group 1 (Control Group, n=15); After intubation, saline infusion will be started. The control group will also be infused with the same volume of saline. ...

Eligibility Criteria

Inclusion

  • ASA (American Society of Anaesthesiologists) I-II-III group who will undergo liver resection surgery,
  • no known history of heart, kidney, hematological disease, peptic ulcer, gastrointestinal bleeding, allergy, chronic pain
  • who agreed to participate in the study

Exclusion

  • Patients with underlying serious cardiovascular disease,
  • patients who cannot cooperate, patients who are allergic to one of the drugs to be used
  • patients who do not want to participate

Key Trial Info

Start Date :

June 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 15 2023

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT06219928

Start Date

June 30 2022

End Date

September 15 2023

Last Update

November 18 2024

Active Locations (1)

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1

Ataturk University

Erzurum, Turkey (Türkiye)