Status:

RECRUITING

SNV1521 in Participants with Advanced Solid Tumors

Lead Sponsor:

Synnovation Therapeutics, Inc.

Conditions:

Advanced Solid Tumor

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

This study is testing a new medicine, SNV1521, for people with advanced cancers. The researchers want to find out if SNV1521 is safe, well-tolerated, and effective in treating solid tumors. They are i...

Eligibility Criteria

Inclusion

  • Advanced or metastatic solid tumor malignancy
  • Evaluable or Measurable disease (RECIST 1.1 Criteria).
  • ECOG Performance Status 0 or 1.
  • Life expectancy \> 3 months

Exclusion

  • History of other malignancy within the past 2 years
  • Prior diagnosis of Myelodysplastic syndrome or Acute Myeloid Leukemia
  • Significant cardiovascular disease within 6 months
  • Significant gastrointestinal disease
  • HIV infection with a CD4+ T-cell count \< 200 cells/μL and/or a detectable viral load
  • Liver dysfunction

Key Trial Info

Start Date :

February 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06220864

Start Date

February 23 2024

End Date

December 1 2026

Last Update

March 13 2025

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Yale University

New Haven, Connecticut, United States, 06520

2

Thomas Jefferson University

Philadelphia, Pennsylvania, United States, 19144

3

Sarah Cannon Research Institute

Nashville, Tennessee, United States, 37203

4

The University of Texas M.D. Anderson Cancer Center

Houston, Texas, United States, 77030